Persica publications

Chronic low back pain, bacterial infection and treatment with antibiotics

Gilligan et al 2021

https://www.thespinejournalonline.com/article/S1529-9430(21)00084-X/fulltext

Intradiscal pharmacokinetics of oral antibiotics to treat Chronic Lower Back Pain

Czaplewski et al 2023

https://www.nature.com/articles/s44259-023-00002-7

Modic changes as seen on MRI are associated with nonspecific chronic lower back pain and disability

Czaplewski et al 2023

https://josr-online.biomedcentral.com/articles/10.1186/s13018-023-03839-w

Preclinical development and characterisation of PP353, a formulation of linezolid for intradiscal administration

Hagger et al 2024

https://onlinelibrary.wiley.com/doi/10.1002/jsp2.70010

Pharmacokinetics of PP353, a formulation of linezolid for intervertebral disc administration, in patients with chronic low back pain and Modic change Type 1: A first-in-human, Phase 1b, open-label, single-dose study

Tripathi et al 2024

https://onlinelibrary.wiley.com/doi/10.1002/jsp2.70009